Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27850347 | 0.81 | CYP19A1 (0.58) | ALDH1A1LMNACYP19A1NPC1RAB9A | |
| SCHEMBL28805659 | 0.78 | HSP90AB1 (0.54) | ALDH1A1LMNACYP19A1MEN1KMT2A | |
| SCHEMBL1719412 | 0.77 | ALDH1A1 (0.75) | ALDH1A1LMNACYP19A1MEN1KMT2A | |
| SCHEMBL24666587 | 0.75 | CYP19A1 (0.57) | ALDH1A1LMNACYP19A1NPC1RAB9A | |
| SCHEMBL11119957 | 0.75 | TYR (0.51) | ALDH1A1LMNACYP19A1HDAC1HDAC3 | |
| SCHEMBL29230705 | 0.74 | ALDH1A1 (0.49) | ALDH1A1LMNACYP19A1NPC1RAB9A | |
| SCHEMBL28103690 | 0.74 | CYP19A1 (0.51) | ALDH1A1LMNACYP19A1NPC1RAB9A | |
| SCHEMBL27958968 | 0.73 | CYP19A1 (0.59) | ALDH1A1LMNACYP19A1NPC1RAB9A | |
| SCHEMBL1838394 | 0.73 | CYP19A1 (0.51) | ALDH1A1LMNACYP19A1NPC1RAB9A | |
| SCHEMBL27644462 | 0.72 | KDM4E (0.48) | ALDH1A1LMNAMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597228-A2 | SUBSTITUTED N-ARYLHETEROCYCLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS | Sanofi-Aventis Deutschland GmbH (DE) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004072025-A2 | SUBSTITUTED N-ARYLHETEROCYCLES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENTS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-08-26 | — | — | WO | disclosed |