Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 18/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207000 | 0.82 | CTSS (0.42) | CTSSCYP3A4CYP2C9FAAHCES1 | |
| SCHEMBL7049552 | 0.73 | CTSS (0.44) | CTSSCYP3A4CYP2C9LMNA | |
| SCHEMBL14563015 | 0.72 | CTSS (0.46) | CTSSCYP3A4CYP2C9FAAHCES1 | |
| SCHEMBL6062804 | 0.70 | CTSS (0.51) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL27663441 | 0.70 | CTSS (0.57) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL14562995 | 0.70 | CTSS (0.48) | CTSSCYP3A4CYP2C9FAAHCES1 | |
| SCHEMBL6062622 | 0.70 | CTSS (0.45) | CTSSCYP3A4CYP2C9FAAHCES1 | |
| SCHEMBL6062611 | 0.70 | CTSS (0.45) | CTSSCYP3A4CYP2C9FAAHCES1 | |
| SCHEMBL8361720 | 0.69 | CTSS (0.44) | CTSSCYP3A4CYP2C9FAAHCES1 | |
| SCHEMBL6076070 | 0.69 | CTSS (0.44) | CTSSCYP3A4CYP2C9FAAHCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288336-A1 | Cysteine protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-12-29 | — | — | US | claimed |
| US-20050288336-A1 | Cysteine protease inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2005-12-29 | — | — | US | disclosed |
| EP-1503997-A1 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003097617-A1 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2003-11-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288336-A1 | Cysteine protease inhibitors | CTSF, CTSS, CTSB | CTSS 2/4885CYP3A4 1957/4885CYP2C9 2308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.