Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205921 | 0.81 | PSEN1 (0.30) | — | |
| SCHEMBL6203188 | 0.76 | PSEN1 (0.31) | — | |
| SCHEMBL4765368 | 0.76 | PSEN1 (0.33) | — | |
| SCHEMBL6587495 | 0.72 | TRPM8 (0.35) | KMT2A | |
| SCHEMBL7011790 | 0.71 | — | — | |
| SCHEMBL5099589 | 0.71 | OPRD1 (0.35) | KMT2A | |
| SCHEMBL6204515 | 0.68 | TSHR (0.31) | — | |
| SCHEMBL4936544 | 0.64 | GHSR (0.37) | — | |
| SCHEMBL4766714 | 0.64 | GHSR (0.37) | — | |
| SCHEMBL4762985 | 0.63 | DDB1 (0.34) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539178-A2 | PROTEASE INHIBITORS | SmithKline Beecham Corporation (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004017911-A2 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-03-04 | — | — | WO | disclosed |