Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6204439 | 0.83 | — | — | |
| SCHEMBL13498788 | 0.82 | P2RX3 (0.35) | — | |
| SCHEMBL16580713 | 0.75 | PDXK (0.48) | PDXK | |
| SCHEMBL6204668 | 0.72 | PDXK (0.37) | PDXK | |
| SCHEMBL4442536 | 0.71 | ALOX5AP (0.31) | — | |
| SCHEMBL6202984 | 0.71 | MAPT (0.42) | — | |
| SCHEMBL7966254 | 0.71 | KDM4E (0.32) | PDXK | |
| SCHEMBL4579208 | 0.71 | NOS3 (0.36) | PDXK | |
| SCHEMBL30238970 | 0.71 | NOS3 (0.36) | PDXK | |
| SCHEMBL17589036 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560832-A1 | PYRIMIDO 4,5-D PYRIMIDINE DERIVATIVES WITH ANTICANCER ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004041822-A1 | PYRIMIDO[4,5-D]PYRIMIDINE DERIVATIVES WITH ANTICANCER ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2004-05-21 | — | — | WO | disclosed |