Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1839710 | 0.84 | ALDH1A1 (0.58) | SMN1; SMN2HTTMAPTKDM4EAPAF1 | |
| SCHEMBL6206310 | 0.79 | CTSS (0.53) | SMN1; SMN2HTTMAPTKDM4EAPAF1 | |
| SCHEMBL24623062 | 0.79 | ALDH1A1 (0.40) | SMN1; SMN2HTTMAPTKDM4EAPAF1 | |
| SCHEMBL2704426 | 0.78 | CTSS (0.52) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL13570375 | 0.76 | HTT (0.50) | SMN1; SMN2HTTMAPTKDM4EAPAF1 | |
| SCHEMBL17033023 | 0.72 | MEN1 (0.53) | HTTMAPTKDM4EAPAF1TDP2 | |
| SCHEMBL5102084 | 0.72 | CYP19A1 (0.49) | SMN1; SMN2HTTMAPTALDH1A1CYP2C19 | |
| SCHEMBL7250646 | 0.71 | ALDH1A1 (0.44) | SMN1; SMN2HTTMAPTKMT2AALDH1A1 | |
| SCHEMBL20179421 | 0.71 | CTSS (0.50) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL14629921 | 0.70 | CXCR2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1508560-A2 | Substituted Phenylketoenols | Bayer CropScience AG (DE) | 2005-02-23 | — | — | EP | disclosed |