Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.53 |
| ▸ | CTSK | P43235 | 4/20 | 0.53 |
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | CTSB | P07858 | 3/20 | 0.49 |
| ▸ | ANO1 | Q5XXA6 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27305627 | 0.90 | CTSS (0.63) | CTSSCTSKCTSLCTSBHTT | |
| SCHEMBL8052194 | 0.87 | CTSS (0.56) | CTSSCTSKCTSLCTSBHTT | |
| SCHEMBL9884896 | 0.80 | ANO1 (0.46) | CTSSCTSKCTSLANO1CNR1 | |
| SCHEMBL6206153 | 0.79 | SMN1; SMN2 (0.47) | SMN1; SMN2HTTKDM4EAPAF1TDP2 | |
| SCHEMBL29642581 | 0.79 | CTSL (0.60) | CTSSCTSKCTSLCTSBANO1 | |
| SCHEMBL18910127 | 0.77 | CTSS (0.59) | CTSSCTSKCTSLCTSBSMN1; SMN2 | |
| SCHEMBL12748569 | 0.76 | ANO1 (0.43) | CTSSCTSKANO1CNR1ALDH1A1 | |
| SCHEMBL14999473 | 0.76 | SMN1; SMN2 (0.40) | CTSSCTSKCTSLCTSBANO1 | |
| SCHEMBL14432213 | 0.76 | ANO1 (0.44) | CTSLANO1CNR1CNR2 | |
| SCHEMBL9883924 | 0.75 | ANO1 (0.43) | CTSLANO1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1508560-A2 | Substituted Phenylketoenols | Bayer CropScience AG (DE) | 2005-02-23 | — | — | EP | disclosed |