Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CD44 | P16070 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29477327 | 0.85 | TAAR1 (0.56) | TAAR1ALDH1A1HPGDLTA4HTSHR | |
| SCHEMBL2090458 | 0.85 | TAAR1 (0.56) | TAAR1ALDH1A1HPGDLTA4HTSHR | |
| SCHEMBL29373097 | 0.85 | CYP3A4 (0.53) | CYP3A4TDP1ALDH1A1HPGDALOX15 | |
| SCHEMBL36019 | 0.85 | CYP3A4 (0.53) | CYP3A4TDP1ALDH1A1HPGDALOX15 | |
| SCHEMBL450599 | 0.85 | CYP3A4 (0.46) | CYP3A4TDP1TAAR1ALDH1A1HPGD | |
| SCHEMBL1759362 | 0.83 | CYP3A4 (0.50) | CYP3A4TDP1ALDH1A1HPGDALOX15 | |
| Hydrochloric Acid SCHEMBL11743462 | 0.83 | CYP3A4 (0.50) | CYP3A4TDP1ALDH1A1HPGDALOX15 | |
| SCHEMBL29772212 | 0.83 | TAAR1 (0.54) | TAAR1ALDH1A1HPGDLTA4HTSHR | |
| Ammonia Solution, Strong SCHEMBL9517239 | 0.83 | CYP3A4 (0.50) | CYP3A4TDP1ALDH1A1HPGDALOX15 | |
| SCHEMBL9719138 | 0.83 | CYP3A4 (0.50) | CYP3A4TDP1ALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2668039-B1 | A LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2015-06-03 | — | — | EP | disclosed |
| WO-2013068966-A2 | COSMETIC COMPOSITION COMPRISING AN UREA OR AMIDE BASED ALPHA-ALKOXYSILANE | L'OREAL (FR) | 2013-05-16 | — | — | WO | disclosed |
| US-20090182143-A1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS, S.A. (CH) | 2009-07-16 | — | — | US | disclosed |
| US-7393846-B2 | Heterocyclic compounds useful for the treatment of inflammatory and allergic disorders | GLENMARK PHARMACEUTICALS, S.A. (CH) | 2008-07-01 | — | — | US | disclosed |
| US-20080146810-A1 | NOVEL TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS S.A. (CH) | 2008-06-19 | — | — | US | disclosed |
| US-7384962-B2 | Heterocyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them | GLENMARK PHARMACEUTICALS S.A. (CH) | 2008-06-10 | — | — | US | disclosed |
| US-7238725-B2 | Tricyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them | GLENMARK PHARMACEUTICALS LTD. (IN) | 2007-07-03 | — | — | US | disclosed |
| US-7223789-B2 | Heterocyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them | GLENMARK PHARMACEUTICALS S.A. (CH) | 2007-05-29 | — | — | US | disclosed |
| US-20070105855-A1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS S.A. (CH) | 2007-05-10 | — | — | US | disclosed |
| US-20070105854-A1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS S.A. (CH) | 2007-05-10 | — | — | US | disclosed |
| EP-0286029-A1 | Alkylation of aromatic amines over A1 exchanged zeolites | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1988-10-12 | — | — | EP | disclosed |
| US-4760184-A | Reacting with alcohol, olefin or diolefin in presence of alkylating catalyst of larger microspores | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1988-07-26 | — | — | US | disclosed |
| US-4740620-A | HIGH SELECTIVITY TO THE ORTHO POSITION | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1988-04-26 | — | — | US | disclosed |
| EP-0245797-A2 | Alkylation of aromatic amines in the presence of non-zeolitic molecular sieves | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1987-11-19 | — | — | EP | disclosed |
| EP-0226781-A1 | Alkylation of aromatic amines in the presence of acidic, crystalline molecular sieves | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1987-07-01 | — | — | EP | disclosed |
| US-4632987-A | FORMYLATION, HYDROLYSIS, CONDENSATION OF BENZENE AND NAPHTHALENE COMPOUNDS | MITSUI TOATSU CHEMICALS INCORPORATED (JP) | 1986-12-30 | — | — | US | disclosed |
| US-4469609-A | OXIDATION RESISTANCE | UNIROYAL, INC. (US) | 1984-09-04 | — | — | US | disclosed |
| EP-0036116-B1 | METHOD OF PREPARING AZO DYESTUFFS | BAYER AG (DE) | 1983-05-18 | — | — | EP | disclosed |
| EP-0036116-A2 | Method of preparing azo dyestuffs | BAYER AG (DE) | 1981-09-23 | — | — | EP | disclosed |
| US-3985376-A | Dye precursors for pressure-sensitive recording material | BASF AKTIENGESELLSCHAFT (DT) | 1976-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090182143-A1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PDE4A, PDE4B, PDE12 | CYP3A4 17/4885TDP1 612/4885TAAR1 1422/4885 |
| US-20080146810-A1 | NOVEL TRICYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LTC4S, TSLP, GPR119 | CYP3A4 594/4885TDP1 4379/4885TAAR1 917/4885 |
| US-20070105854-A1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PDE4A, PDE4B, PDE12 | CYP3A4 17/4885TDP1 612/4885TAAR1 1422/4885 |
| US-20070105855-A1 | NOVEL HETEROCYCLIC COMPOUNDS USEFUL FOR THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISORDERS: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PDE4A, PDE4B, PDE12 | CYP3A4 17/4885TDP1 612/4885TAAR1 1422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.