Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12476194 | 0.81 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ATDP1MAPT | |
| SCHEMBL12476188 | 0.79 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2ATDP1MAPT | |
| SCHEMBL31694579 | 0.78 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ATDP1MAPT | |
| SCHEMBL6206638 | 0.77 | ATM (0.48) | ALDH1A1MEN1KMT2ATDP1MAPT | |
| SCHEMBL6208230 | 0.77 | ATM (0.48) | ALDH1A1MEN1KMT2ATDP1MAPT | |
| SCHEMBL6204759 | 0.77 | TDP1 (0.51) | ALDH1A1MEN1KMT2ATDP1MAPT | |
| SCHEMBL6206051 | 0.77 | TDP1 (0.48) | ALDH1A1MEN1KMT2ATDP1MAPT | |
| SCHEMBL6206062 | 0.77 | ATM (0.51) | MEN1KMT2ATDP1MAPTRAB9A | |
| SCHEMBL6205994 | 0.77 | TDP1 (0.48) | ALDH1A1MEN1KMT2ATDP1MAPT | |
| SCHEMBL12988187 | 0.76 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2ATDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532128-A1 | INHIBITORS OF HCV NS5B POLYMERASE | Pharmacia & Upjohn Company LLC (US) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002977-A1 | INHIBITORS OF HCV NS5B POLYMERASE | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-01-08 | — | — | WO | disclosed |