Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205997 | 0.84 | ELANE (0.43) | ELANECYP1A2PARP10NSD2TDP1 | |
| SCHEMBL7758087 | 0.75 | ELANE (0.46) | ELANECYP1A2NSD2TDP1MAPT | |
| SCHEMBL3852977 | 0.72 | ELANE (0.51) | ELANEPARP10NSD2TDP1MAPT | |
| SCHEMBL28856143 | 0.71 | ELANE (0.51) | ELANECYP1A2PARP10NSD2TDP1 | |
| SCHEMBL17102368 | 0.71 | ELANE (0.46) | ELANEPARP10NSD2TDP1MAPT | |
| SCHEMBL6204762 | 0.71 | ELANE (0.53) | ELANECYP1A2PARP10NSD2TDP1 | |
| SCHEMBL4333100 | 0.71 | ELANE (0.48) | ELANECYP1A2TDP1MAPTL3MBTL1 | |
| SCHEMBL461096 | 0.69 | ELANE (0.53) | ELANECYP1A2PARP10NSD2TDP1 | |
| SCHEMBL6205992 | 0.69 | ELANE (0.43) | ELANECYP1A2PARP10NSD2TDP1 | |
| Phosphine SCHEMBL28214722 | 0.69 | ELANE (0.45) | ELANECYP1A2PARP10NSD2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532128-A1 | INHIBITORS OF HCV NS5B POLYMERASE | Pharmacia & Upjohn Company LLC (US) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004002977-A1 | INHIBITORS OF HCV NS5B POLYMERASE | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-01-08 | — | — | WO | disclosed |