Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670711 | 0.91 | ALDH1A1 (0.45) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL2614740 | 0.89 | ALDH1A1 (0.48) | ALDH1A1TPMTDAORXRARXRB | |
| SCHEMBL27453576 | 0.84 | TPMT (0.43) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL27383639 | 0.82 | KDM4E (0.44) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL21450669 | 0.82 | ALDH1A1 (0.35) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL1039738 | 0.82 | TPMT (0.45) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29240829 | 0.81 | GABRP (0.47) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL28770769 | 0.80 | TPMT (0.43) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL27712924 | 0.80 | ALDH1A1 (0.42) | ALDH1A1GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL31384464 | 0.80 | ALDH1A1 (0.39) | ALDH1A1GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315719-A4 | MULTIVALENT NEURAMINIDASE INHIBITOR CONJUGATES | BIOTA SCIENT MANAGEMENT (AU) | 2005-07-20 | — | — | EP | disclosed |
| EP-1315719-A1 | MULTIVALENT NEURAMINIDASE INHIBITOR CONJUGATES | BIOTA SCIENTIFIC MANAGEMENT PTY. LTD. (AU) | 2003-06-04 | — | — | EP | disclosed |
| WO-2002020514-A1 | MULTIVALENT NEURAMINIDASE INHIBITOR CONJUGATES | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2002-03-14 | — | — | WO | disclosed |