Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206768 | 1.00 | MAOB (0.52) | MAOBSMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL6207441 | 0.86 | TDP1 (0.46) | SMN1; SMN2RAB9ANPC1POLBL3MBTL1 | |
| SCHEMBL6207388 | 0.81 | ALDH1A1 (0.43) | SMN1; SMN2RAB9ANPC1POLBPARP10 | |
| SCHEMBL6208081 | 0.80 | RAB9A (0.59) | MAOBSMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL6207298 | 0.80 | RAB9A (0.59) | MAOBSMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL6207300 | 0.79 | RAB9A (0.58) | MAOBSMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL6210392 | 0.79 | RAB9A (0.58) | MAOBSMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL6208904 | 0.79 | RAB9A (0.58) | MAOBSMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL6539741 | 0.78 | TNF (0.47) | MAOBSMN1; SMN2RAB9ANPC1POLB | |
| Hydrochloric Acid SCHEMBL6207459 | 0.78 | RAB9A (0.57) | MAOBSMN1; SMN2RAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583749-A1 | OXAZOLE DERIVATIVES AS INHIBITORS OF CYCLOOXYGENASE | Astellas Pharma Inc. (JP) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004065374-A1 | OXAZOLE DERIVATIVES AS INHIBITORS OF CYCLOOXYGENASE | ASTELLAS PHARMA INC. (JP) | 2004-08-05 | — | — | WO | disclosed |