Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 9/20 | 0.52 |
| ▸ | CA2 | P00918 | 9/20 | 0.52 |
| ▸ | CA7 | P43166 | 9/20 | 0.52 |
| ▸ | CA9 | Q16790 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | APAF1 | O14727 | 5/20 | 0.40 |
| ▸ | TDP2 | O95551 | 4/20 | 0.40 |
| ▸ | NSD2 | O96028 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206534 | 0.83 | NPSR1 (0.48) | ALDH1A1L3MBTL1TSHRHTTKMT2A | |
| SCHEMBL27467210 | 0.77 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1TSHRMAPTAPAF1 | |
| SCHEMBL27892920 | 0.74 | NPC1 (0.40) | ALDH1A1TSHRMAPTHTTKMT2A | |
| SCHEMBL17986 | 0.72 | CA1 (1.00) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL29350272 | 0.72 | CA1 (1.00) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL3658029 | 0.72 | CA1 (1.00) | CA1CA2CA7CA9ALDH1A1 | |
| SCHEMBL27558619 | 0.71 | RAB9A (0.53) | CA1CA2CA9ALDH1A1L3MBTL1 | |
| SCHEMBL6889531 | 0.70 | NPSR1 (0.56) | CA1CA2ALDH1A1L3MBTL1MAPT | |
| Ammonia Solution, Strong SCHEMBL1286269 | 0.70 | CA1 (0.94) | CA1CA2CA7CA9ALDH1A1 | |
| Water SCHEMBL592691 | 0.70 | CA1 (0.94) | CA1CA2CA7CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566445-B1 | Derivatives of indane 1,3-dione and indane-1,2,3-trione, processes for their preparation and their application in therapy | INNOTHERA LAB SA (FR) | 1996-02-07 | — | — | EP | disclosed |