Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 6/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206687 | 0.87 | PDK2 (0.47) | PDK2KMT2AL3MBTL1LDHAPDK1 | |
| SCHEMBL14175013 | 0.79 | KMT2A (0.53) | PDK2KMT2AL3MBTL1LDHAPDK1 | |
| SCHEMBL5068119 | 0.78 | L3MBTL1 (0.58) | PDK2KMT2AL3MBTL1LDHAPDK1 | |
| SCHEMBL19331445 | 0.75 | TYR (0.56) | — | |
| SCHEMBL28924629 | 0.70 | PDK2 (0.47) | PDK2KMT2AL3MBTL1LDHAPDK1 | |
| SCHEMBL8346737 | 0.67 | KDM4E (0.57) | — | |
| SCHEMBL14132351 | 0.66 | LMNA (0.40) | KMT2A | |
| Bromide SCHEMBL4417981 | 0.66 | KDM4E (0.56) | — | |
| SCHEMBL3562641 | 0.66 | RAB9A (0.49) | KMT2A | |
| SCHEMBL4160504 | 0.65 | TYR (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1585481-A2 | PYRAZOLOPYRIMIDINE COMPOUND AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004064721-A2 | A PYRAZOLOPYRIMIDINE COMPOUND AND A PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 2004-08-05 | — | — | WO | disclosed |