Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 14/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207242 | 0.94 | ADORA2A (0.47) | WDR5ADORA2AELANE | |
| SCHEMBL6206094 | 0.86 | SNCA (0.56) | WDR5CYP11B1CYP11B2POLB | |
| SCHEMBL6205208 | 0.81 | CHRM3 (0.53) | ADORA2APOLBRAB9A | |
| SCHEMBL6204872 | 0.80 | POLB (0.47) | WDR5ADORA2AELANEPOLBRAB9A | |
| SCHEMBL6205541 | 0.79 | MEN1 (0.52) | ADORA2APOLBRAB9A | |
| SCHEMBL6205245 | 0.79 | HPGD (0.55) | ADORA2APOLBRAB9A | |
| SCHEMBL6204032 | 0.79 | POLB (0.68) | POLBRAB9A | |
| SCHEMBL6207258 | 0.79 | POLB (0.51) | ADORA2APOLBRAB9A | |
| SCHEMBL6204733 | 0.78 | SNCA (0.62) | WDR5ADORA2ACYP11B1CYP11B2POLB | |
| SCHEMBL6206374 | 0.74 | ADORA2A (0.58) | ADORA2APOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177177-B1 | SUBSTITUTED 4-OXO-QUINOLINE-3-CARBOXAMIDES: GABA BRAIN RECEPTOR LIGANDS | NEUROGEN CORP (US) | 2005-02-23 | — | — | EP | claimed |