Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206731 | 0.83 | ALDH1A1 (0.42) | TSHRTDP1ALDH1A1CHRM2CHRM4 | |
| SCHEMBL6208122 | 0.82 | ALOX15 (0.39) | TSHRTDP1ALDH1A1CHRM2CHRM4 | |
| SCHEMBL18110352 | 0.79 | TSHR (0.31) | TSHRTDP1ALDH1A1 | |
| SCHEMBL6208223 | 0.77 | — | — | |
| SCHEMBL10521929 | 0.74 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL8028244 | 0.74 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL8028249 | 0.74 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL8028253 | 0.74 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL6207226 | 0.74 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL5225784 | 0.71 | TSHR (0.42) | TSHRALDH1A1CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979244-B1 | NOVEL CYCLOSPORIN DERIVATIVES, PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA SA (FR) | 2005-03-02 | — | — | EP | disclosed |