Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.39 |
| ▸ | HPGDS | O60760 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL619715 | 0.90 | MCHR1 (0.41) | KCNH2KCNQ1CACNA1CHTR7MCHR1 | |
| SCHEMBL621308 | 0.89 | KCNH2 (0.39) | KCNH2KCNQ1CACNA1CMCHR1HPGDS | |
| SCHEMBL622377 | 0.88 | HPGDS (0.40) | KCNH2KCNQ1CACNA1CHTR7HPGDS | |
| SCHEMBL621354 | 0.85 | MCHR1 (0.40) | KCNH2KCNQ1CACNA1CHTR7MCHR1 | |
| SCHEMBL621527 | 0.82 | HTR7 (0.45) | KCNH2HTR7MCHR1HPGDS | |
| SCHEMBL622330 | 0.81 | KCNH2 (0.43) | KCNH2KCNQ1CACNA1C | |
| Hydrochloric Acid SCHEMBL6079190 | 0.81 | SLC2A1 (0.51) | KCNH2 | |
| SCHEMBL622663 | 0.79 | KCNH2 (0.42) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL619920 | 0.78 | KDM4E (0.39) | KCNH2KCNQ1CACNA1CMCHR1HPGDS | |
| SCHEMBL619908 | 0.78 | ALDH1A1 (0.38) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040957-A1 | Novel Bicyclic Antibiotics | BASILEA PHARMACEUTICA AG | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040957-A1 | Novel Bicyclic Antibiotics | C5, C1S, CBR3 | KCNH2 488/4885KCNQ1 3195/4885CACNA1C 1896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.