SCHEMBL6207098

SCHEMBL6207098

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nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
RNPEP Q9H4A4 1/20 0.32
FOLH1 Q04609 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6208223 0.80
SCHEMBL6207226 0.72 ALDH1A1 (0.34) RNPEP
SCHEMBL8028253 0.72 ALDH1A1 (0.34) RNPEP
SCHEMBL8028249 0.72 ALDH1A1 (0.34) RNPEP
SCHEMBL10521929 0.72 ALDH1A1 (0.34) RNPEP
SCHEMBL8028244 0.72 ALDH1A1 (0.34) RNPEP
SCHEMBL2230911 0.66 TP53 (0.41)
SCHEMBL8351936 0.66 TP53 (0.41)
SCHEMBL2230916 0.66 TP53 (0.41)
SCHEMBL27777155 0.65 TP53 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0979244-B1 NOVEL CYCLOSPORIN DERIVATIVES, PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AVENTIS PHARMA SA (FR) 2005-03-02 EP claimed
EP-0979244-B1 NOVEL CYCLOSPORIN DERIVATIVES, PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AVENTIS PHARMA SA (FR) 2005-03-02 EP disclosed