Geraldol

Geraldol

SCHEMBL620712

COc1cc(-c2oc3cc(O)ccc3c(=O)c2O)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 9/20 1.00
KMT2A Q03164 9/20 1.00
MAPT P10636 8/20 1.00
KDM4E B2RXH2 7/20 1.00
CYP3A4 P08684 7/20 1.00
CASP1 P29466 7/20 1.00
CASP7 P55210 7/20 1.00
HSD17B10 Q99714 6/20 1.00
TP53 P04637 6/20 1.00
ALDH1A1 P00352 6/20 1.00
HPGD P15428 5/20 1.00
MAPK1 P28482 3/20 1.00
LMNA P02545 3/20 1.00
ALOX15 P16050 3/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
ABCB1 P08183 1/20 0.84
CDK5 Q00535 2/20 0.72
CDK5R1 Q15078 2/20 0.72
XDH P47989 2/20 0.72
CYP2C9 P11712 2/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Geraldol SCHEMBL31122383 1.00 MEN1 (1.00) MEN1KMT2AMAPTKDM4ECYP3A4
Geraldol SCHEMBL29394734 1.00 MEN1 (1.00) MEN1KMT2AMAPTKDM4ECYP3A4
SCHEMBL31675757 0.91 ABCB1 (1.00) MEN1KMT2AMAPTKDM4ECYP3A4
SCHEMBL4650613 0.91 ABCB1 (1.00) MEN1KMT2AMAPTKDM4ECYP3A4
SCHEMBL4101098 0.90 ABCB1 (0.84) MEN1KMT2AMAPTKDM4ECYP3A4
SCHEMBL29870196 0.88 ABCB1 (0.81) MEN1KMT2AMAPTKDM4ECYP3A4
SCHEMBL14259665 0.87 MAPT (0.77) MEN1KMT2AMAPTKDM4ECYP3A4
SCHEMBL29358799 0.87 MAPT (0.77) MEN1KMT2AMAPTKDM4ECYP3A4
SCHEMBL15844041 0.86 KDM4E (0.83) MEN1KMT2AMAPTKDM4ECYP3A4
SCHEMBL4649883 0.86 ABCB1 (0.77) MEN1KMT2AMAPTKDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 186 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4698662-A2 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES AskBio Inc. (US) 2026-02-25 EP claimed
EP-2603098-B1 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER FIRMENICH INCORPORATED (US) 2025-08-06 EP claimed
WO-2024220449-A9 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES AskBio Inc. (US) 2025-04-03 WO claimed
WO-2024220449-A2 REGULATABLE CONTROLLED EXPRESSION OF A TRANSGENE IN PRIMATES ASKLEPIOS BIOPHARMACEUTICAL, INC. (US) 2024-10-24 WO claimed
US-10244779-B2 Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer SENOMYX, INC. (US) 2019-04-02 US claimed
WO-2018172436-A1 FORMULATIONS COMPRISING ACTIVE AGENTS DERIVED FROM THE PLANT MURRAYA KOENIGII WIERNSPERGER NICOLAS (FR) 2018-09-27 WO claimed
EP-2544554-B1 METHOD FOR STABILIZING WATER INSOLUBLE BIOACTIVE COMPOUND AQUEOUS DISPERSIONS STOKELY VAN CAMP INC (US) 2016-11-30 EP claimed
US-20150245642-A1 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER FIRMENICH INCORPORATED 2015-09-03 US claimed
US-9000054-B2 Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer SENOMYX, INC. (US) 2015-04-07 US claimed
EP-2603098-A2 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER Senomyx, Inc. (US) 2013-06-19 EP claimed
US-20080311497-A1 HOLE BLOCKING LAYER CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2008-12-18 US claimed
US-7462433-B2 Undercoat layer containing charge transfer molecule, andTiO2; imaging layer; charge transfer molecule complexes with the TiO2 to form coordination bonds and the coordination bonds provide a reduction in ghosting; electrophotographic imaging members; improved image quality XEROX CORPORATION (US) 2008-12-09 US claimed
US-20070110851-A1 Beverage composition and method of preventing degradation of vitamins in beverages PEPSICO, INC. 2007-05-17 US claimed
EP-1782701-A1 Beverage composition and method of preventing degradation of vitamins in beverages PepsiCo, Inc. (US) 2007-05-09 EP claimed
US-20070048639-A1 Undercoat layer containing charge transfer molecule, andTiO2; imaging layer; charge transfer molecule complexes with the TiO2 to form coordination bonds and the coordination bonds provide a reduction in ghosting; electrophotographic imaging members; improved image quality XEROX CORPORATION (US) 2007-03-01 US claimed
US-6872771-B1 Tire with rubber containing flavone THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-03-29 US claimed
US-20040091589-A1 Prevention of synthetic color fading in beverages using botanically derived color stabilizers PEPSICO, INC. 2004-05-13 US claimed
JP-2003504327-A 2003-02-04 JP claimed
EP-1223928-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS Prendergast, Patrick Thomas (IE) 2002-07-24 EP claimed
WO-2001003681-A2 USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS PRENDERGAST PATRICK T (IE) 2001-01-18 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10244779-B2 Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer TFEB, TREH, SLC2A8 MEN1 2269/4885KMT2A 740/4885MAPT 1864/4885
US-20150245642-A1 METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER TFEB, TREH, SLC2A8 MEN1 2269/4885KMT2A 740/4885MAPT 1864/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.