Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6207130 | 1.00 | RAB9A (0.49) | RAB9ANPC1KMT2AMAPTLMNA | |
| SCHEMBL6208861 | 0.78 | NPC1 (0.48) | RAB9ANPC1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6208862 | 0.78 | NPC1 (0.48) | RAB9ANPC1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL15871029 | 0.76 | LPO (0.48) | RAB9ANPC1KMT2AMAPTLMNA | |
| SCHEMBL8906261 | 0.71 | RAB9A (0.47) | RAB9ANPC1KMT2AMAPTLMNA | |
| SCHEMBL16364089 | 0.70 | KMT2A (0.55) | RAB9ANPC1KMT2AMAPTLMNA | |
| SCHEMBL6208939 | 0.68 | HRH4 (0.40) | RAB9ANPC1KMT2AMAPTLMNA | |
| SCHEMBL2457803 | 0.67 | KDM4E (0.47) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL2457805 | 0.67 | KDM4E (0.47) | RAB9ANPC1KMT2AMAPTMEN1 | |
| SCHEMBL3437039 | 0.67 | TDP1 (0.56) | RAB9ANPC1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1349839-B1 | PHENYLETHENYL OR PHENYLETHINYL DERIVATIVES AS GLUTAMATE RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2005-02-09 | — | — | EP | claimed |