Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7810486 | 0.72 | LMNA (0.46) | RAB9ANPC1LMNAMAPTMEN1 | |
| SCHEMBL6207130 | 0.71 | RAB9A (0.49) | RAB9ANPC1LMNAMAPTMEN1 | |
| SCHEMBL6207129 | 0.71 | RAB9A (0.49) | RAB9ANPC1LMNAMAPTMEN1 | |
| SCHEMBL11454521 | 0.67 | TDP1 (0.60) | RAB9ANPC1LMNAMAPTMEN1 | |
| SCHEMBL11241432 | 0.66 | MAPT (0.54) | RAB9ANPC1LMNAMAPTMEN1 | |
| SCHEMBL11241434 | 0.66 | MAPT (0.54) | RAB9ANPC1LMNAMAPTMEN1 | |
| SCHEMBL672680 | 0.66 | TDP1 (0.58) | RAB9ANPC1LMNAMAPTMEN1 | |
| SCHEMBL672679 | 0.66 | TDP1 (0.58) | RAB9ANPC1LMNAMAPTMEN1 | |
| SCHEMBL1689790 | 0.66 | TDP1 (0.58) | RAB9ANPC1LMNAMAPTMEN1 | |
| SCHEMBL29444183 | 0.66 | TDP1 (0.58) | RAB9ANPC1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681755-A | SOLUTION COMPRISING METAL IONS, MOLAR EXCESS OF HISTIDINE OR IMIDAZOLE COMPLEXING AGENT, REDUCING AGENT; QUALITATIVE OR QUANTITATIVE DETERMINATION OF COMPONENTS OF AGGREGATE | JANSSEN PHARMACEUTICA N.V. (BE) | 1997-10-28 | — | — | US | disclosed |