Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 7/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | GHSR | Q92847 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6030364 | 0.90 | EPHX1 (0.45) | EPHX1ALDH1A1HTTZDHHC2GHSR | |
| SCHEMBL6030342 | 0.82 | ALDH1A1 (0.41) | EPHX1ALDH1A1HTTPOLBKMT2A | |
| SCHEMBL6207149 | 0.81 | EPHX1 (0.45) | EPHX1ALDH1A1HTTNAAAKMT2A | |
| SCHEMBL6208748 | 0.79 | EPHX1 (0.47) | EPHX1ALDH1A1HTTPOLBEPHX2 | |
| SCHEMBL6205569 | 0.78 | EPHX1 (0.45) | EPHX1ALDH1A1HTTEPHX2NAAA | |
| SCHEMBL6205626 | 0.78 | EPHX1 (0.45) | EPHX1ALDH1A1HTTEPHX2NAAA | |
| SCHEMBL6030205 | 0.76 | ALDH1A1 (0.46) | EPHX1ALDH1A1HTTEPHX2KMT2A | |
| SCHEMBL6030764 | 0.73 | EPHX1 (0.46) | EPHX1ALDH1A1HTTPOLBNAAA | |
| SCHEMBL6030362 | 0.72 | EPHX1 (0.46) | EPHX1ALDH1A1HTTPOLBNAAA | |
| SCHEMBL6030484 | 0.71 | MAPT (0.48) | EPHX1ALDH1A1HTTPOLBEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1467978-A4 | PANCREATIC LIPASE INHIBITOR COMPOUNDS, THEIR SYNTHESIS AND USE | OSI PHARM INC (US) | 2005-11-02 | — | — | EP | disclosed |
| EP-1467978-A1 | PANCREATIC LIPASE INHIBITOR COMPOUNDS, THEIR SYNTHESIS AND USE | OSI Pharmaceuticals, Inc. (US) | 2004-10-20 | — | — | EP | disclosed |
| WO-2003053944-A1 | PANCREATIC LIPASE INHIBITOR COMPOUNDS, THEIR SYNTHESIS AND USE | OSI PHARMACEUTICALS, INC. (US) | 2003-07-03 | — | — | WO | disclosed |