Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3118444 | 0.76 | GAA (0.41) | GAAMAPK1SMN1; SMN2 | |
| SCHEMBL6190252 | 0.74 | MEN1 (0.34) | — | |
| SCHEMBL1919278 | 0.71 | NOTUM (0.37) | — | |
| SCHEMBL1950287 | 0.67 | LMNA (0.32) | SMN1; SMN2 | |
| SCHEMBL2442751 | 0.66 | ALDH1A1 (0.39) | HPGDSMN1; SMN2 | |
| SCHEMBL3486703 | 0.66 | NOTUM (0.63) | HPGDMAPK1SMN1; SMN2 | |
| SCHEMBL5688247 | 0.65 | PLAU (0.31) | — | |
| SCHEMBL5685247 | 0.65 | PLAU (0.31) | — | |
| SCHEMBL578027 | 0.65 | MAOA (0.59) | OPRM1 | |
| SCHEMBL3341089 | 0.65 | KDM4E (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549639-A1 | SULPHONAMIDE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2005-07-06 | — | — | EP | claimed |
| WO-2004031181-A1 | SULFONAMIDE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | GLAXO GROUP LIMITED (GB) | 2004-04-15 | — | — | WO | claimed |