Sugi Predict

Sugi Predict / Compounds / SCHEMBL6207310

SCHEMBL6207310

SCHEMBL6207310

CCN1C(=O)c2ccc(N)cc2C1=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.57
▸ CASP1 P29466 5/20 0.55
▸ HSD17B10 Q99714 4/20 0.55
▸ MEN1 O00255 4/20 0.55
▸ KMT2A Q03164 4/20 0.55
▸ GAA P10253 3/20 0.55
▸ ALDH1A1 P00352 8/20 0.54
▸ TSHR P16473 4/20 0.54
▸ NPC1 O15118 4/20 0.54
▸ RAB9A P51151 4/20 0.54
▸ CASP7 P55210 3/20 0.54
▸ RPS6KA2 Q15349 1/20 0.52
▸ ANPEP P15144 2/20 0.51
▸ DPP4 P27487 1/20 0.51
▸ CYP1B1 Q16678 3/20 0.50
▸ MAPT P10636 2/20 0.50
▸ MAPK1 P28482 2/20 0.50
▸ ALOX15 P16050 1/20 0.50
▸ NPSR1 Q6W5P4 1/20 0.50
▸ USP2 O75604 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30070294 1.00 POLB (0.57) POLBCASP1HSD17B10MEN1KMT2A
SCHEMBL8005568 0.85 CASP1 (0.60) POLBCASP1HSD17B10MEN1KMT2A
SCHEMBL2651666 0.82 HSD17B10 (0.66) CASP1HSD17B10MEN1KMT2AGAA
SCHEMBL11878800 0.81 HSD17B10 (0.64) CASP1HSD17B10MEN1KMT2AGAA
SCHEMBL6955085 0.81 CASP1 (0.55) POLBCASP1HSD17B10MEN1KMT2A
SCHEMBL13143053 0.80 CASP1 (0.53) CASP1HSD17B10MEN1KMT2AGAA
SCHEMBL14560519 0.80 HSD17B10 (0.62) CASP1HSD17B10MEN1KMT2AGAA
SCHEMBL15149207 0.79 CASP1 (0.50) POLBCASP1HSD17B10MEN1KMT2A
SCHEMBL10054041 0.78 POLB (0.59) POLBMEN1KMT2AGAAALDH1A1
SCHEMBL3582064 0.78 KDM4E (0.69) CASP1HSD17B10MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115572282-B Pyrazole amide compound containing aromatic heterocyclic structure, and preparation method and application thereof 华东理工大学 2024-07-09 — — CN disclosed
CN-111303005-B Coupling component containing phthalimide structure, preparation method and application thereof 乌海青石化学有限公司 2023-09-08 — — CN disclosed
CN-115572282-A Pyrazole amide compound containing aromatic heterocyclic structure, and preparation method and application thereof 华东理工大学 2023-01-06 — — CN disclosed
CN-111303005-A Coupling component containing phthalimide structure and preparation method and application thereof 乌海青石化学有限公司 2020-06-19 — — CN disclosed
US-8273167-B2 Pigment dispersion composition, curable color composition, color filter and method for producing the same FUJIFILM CORPORATION (JP) 2012-09-25 — — US disclosed
US-8227618-B2 Amine-derivatives having NPY Y5 receptor antagonistic activity and the uses thereof SHIONOGI & CO., LTD. (JP) 2012-07-24 — — US disclosed
US-20110263540-A1 SMALL-MOLECULE INHIBITORS OF PROTEIN SYNTHESIS INACTIVATING TOXINS MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH 2011-10-27 — — US disclosed
EP-1358274-B1 PHTHALIMIDYL AZO DYES, PROCESS FOR THEIR PREPARATION AND THE USE THEREOF HUNTSMAN ADV MAT SWITZERLAND (CH) 2011-01-26 — — EP disclosed
US-20100273841-A1 AMINE-DERIVATIVES HAVING NPY Y5 RECEPTOR ANTAGONISTIC ACTIVITY AND THE USES THEREOF SHIONOGI & CO., LTD. (JP) 2010-10-28 — — US disclosed
US-20100256252-A1 PIGMENT DISPERSION COMPOSITION, CURABLE COLOR COMPOSITION, COLOR FILTER AND METHOD FOR PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2010-10-07 — — US disclosed
WO-1999036402-A1 PROCESS FOR PREPARING SPARINGLY SOLUBLE AROMATIC AMINES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 1999-07-22 — — WO disclosed
EP-0898562-A1 HYDROXAMIC ACID DERIVATIVES FOR USE WITH THE TREATMENT OF DISEASES RELATED TO CONNECTIVE TISSUE DEGRADATION PHARMACIA & UPJOHN COMPANY (US) 1999-03-03 — — EP disclosed
WO-1997032846-A1 HYDROXAMIC ACID DERIVATIVES FOR USE WITH THE TREATMENT OF DISEASES RELATED TO CONNECTIVE TISSUE DEGRADATION PHARMACIA & UPJOHN COMPANY (US) 1997-09-12 — — WO disclosed
US-4734490-A TEXTILE DYEING AND PRINTING CIBA-GEIGY CORPORATION (US) 1988-03-29 — — US disclosed
EP-0051563-B1 MONO-AZO COMPOUNDS CIBA-GEIGY AG (CH) 1985-04-24 — — EP disclosed
EP-0051563-A1 Mono-azo compounds CIBA-GEIGY AG (CH) 1982-05-12 — — EP disclosed
US-4324719-A YELLOW TO BLUE SHADES ON NYLON CARPET EASTMAN KODAK COMPANY (US) 1982-04-13 — — US disclosed
US-4039522-A Phthalimidyl-azo-m-acylamido-n-substituted aniline compounds and polyester fibers dyed therewith EASTMAN KODAK COMPANY (US) 1977-08-02 — — US disclosed
US-4012372-A MONOAZO DISPERSE DYES EASTMAN KODAK COMPANY (US) 1977-03-15 — — US disclosed
US-3980634-A Phthalimidyl-azo aniline type compounds and polyester fibers dyed therewith EASTMAN KODAK COMPANY (US) 1976-09-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100273841-A1 AMINE-DERIVATIVES HAVING NPY Y5 RECEPTOR ANTAGONISTIC ACTIVITY AND THE USES THEREOF NPY5R, NPY1R, NPY2R POLB 4070/4885CASP1 3557/4885HSD17B10 638/4885
US-20110263540-A1 SMALL-MOLECULE INHIBITORS OF PROTEIN SYNTHESIS INACTIVATING TOXINS MRPS27, MRPS22, MRPS23 POLB 1398/4885CASP1 3712/4885HSD17B10 3735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.