Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 5/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | CASP7 | P55210 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17077235 | 0.81 | HSD17B10 (0.64) | CASP1HSD17B10MEN1KMT2AGAA | |
| SCHEMBL30070294 | 0.81 | POLB (0.57) | CASP1HSD17B10MEN1KMT2AGAA | |
| SCHEMBL6207310 | 0.81 | POLB (0.57) | CASP1HSD17B10MEN1KMT2AGAA | |
| SCHEMBL11045205 | 0.80 | CASP3 (0.56) | CASP1HSD17B10MEN1KMT2AGAA | |
| SCHEMBL8005568 | 0.78 | CASP1 (0.60) | CASP1HSD17B10MEN1KMT2AGAA | |
| SCHEMBL3582064 | 0.78 | KDM4E (0.69) | CASP1HSD17B10MEN1KMT2AGAA | |
| SCHEMBL2901880 | 0.78 | ALDH1A1 (0.55) | CASP1HSD17B10MEN1KMT2AGAA | |
| SCHEMBL10663245 | 0.78 | CASP1 (0.56) | CASP1HSD17B10MEN1KMT2AGAA | |
| SCHEMBL10661667 | 0.78 | CASP1 (0.52) | CASP1HSD17B10MEN1KMT2AGAA | |
| SCHEMBL6957181 | 0.77 | PARK7 (0.45) | HSD17B10NPC1RAB9ARPS6KA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0898562-B1 | HYDROXAMIC ACID DERIVATIVES FOR USE WITH THE TREATMENT OF DISEASES RELATED TO CONNECTIVE TISSUE DEGRADATION | UPJOHN CO (US) | 2003-01-22 | — | — | EP | claimed |
| CN-1210517-A | Hydroxamic acid derivatives for use with treatment of diseases related to connective tissue degradation | UPJOHN CO (US) | 1999-03-10 | — | — | CN | claimed |
| EP-0898562-A1 | HYDROXAMIC ACID DERIVATIVES FOR USE WITH THE TREATMENT OF DISEASES RELATED TO CONNECTIVE TISSUE DEGRADATION | PHARMACIA & UPJOHN COMPANY (US) | 1999-03-03 | — | — | EP | claimed |
| US-5712300-A | ENZYME INHIBITOR | PHARMACIA & UPJOHN COMPANY (US) | 1998-01-27 | — | — | US | claimed |
| WO-1997032846-A1 | HYDROXAMIC ACID DERIVATIVES FOR USE WITH THE TREATMENT OF DISEASES RELATED TO CONNECTIVE TISSUE DEGRADATION | PHARMACIA & UPJOHN COMPANY (US) | 1997-09-12 | — | — | WO | claimed |
| EP-0898562-B1 | HYDROXAMIC ACID DERIVATIVES FOR USE WITH THE TREATMENT OF DISEASES RELATED TO CONNECTIVE TISSUE DEGRADATION | UPJOHN CO (US) | 2003-01-22 | — | — | EP | disclosed |
| CN-1210517-A | Hydroxamic acid derivatives for use with treatment of diseases related to connective tissue degradation | UPJOHN CO (US) | 1999-03-10 | — | — | CN | disclosed |
| US-5712300-A | ENZYME INHIBITOR | PHARMACIA & UPJOHN COMPANY (US) | 1998-01-27 | — | — | US | disclosed |