SCHEMBL6207340

SCHEMBL6207340

CC(C)CCN(CCC(C)C)C(=O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.51
ALDH1A1 P00352 3/20 0.51
LPAR1 Q92633 2/20 0.50
LPAR5 Q9H1C0 2/20 0.50
MAPT P10636 2/20 0.49
NPC1 O15118 1/20 0.49
MAPK1 P28482 1/20 0.49
HTT P42858 1/20 0.49
RAB9A P51151 1/20 0.49
ATM Q13315 1/20 0.49
F2 P00734 1/20 0.48
F10 P00742 1/20 0.48
F7 P08709 1/20 0.48
MLYCD O95822 1/20 0.46
CASR P41180 1/20 0.45
GAA P10253 1/20 0.44
TRPM8 Q7Z2W7 1/20 0.44
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
PGR P06401 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8806252 0.91 HPGD (0.47) HPGDALDH1A1LPAR1LPAR5MAPT
SCHEMBL1004360 0.85 MLYCD (0.62) HPGDALDH1A1LPAR1LPAR5MAPT
SCHEMBL3455752 0.85 LPAR1 (0.57) LPAR1LPAR5F2F10F7
SCHEMBL16941093 0.84 NAMPT (0.56) MAPTNPC1MAPK1HTTRAB9A
SCHEMBL3456000 0.83 LPAR1 (0.47) HPGDALDH1A1LPAR1LPAR5MAPT
SCHEMBL23791942 0.82 HTR1A (0.46) HPGDALDH1A1MAPTNPC1MAPK1
SCHEMBL12687787 0.82 MLYCD (0.44) HPGDLPAR1LPAR5HTTF2
SCHEMBL1169177 0.81 MEN1 (0.50) ALDH1A1LPAR1LPAR5NPC1RAB9A
SCHEMBL14087384 0.81 ADRA2C (0.59) HPGDALDH1A1MAPTNPC1MAPK1
SCHEMBL19404639 0.80 TP53 (0.51) HPGDALDH1A1MAPTMLYCDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9518150-B2 Resin composition, stretched film, circularly polarizing plate, and image display device MITSUBISHI CHEMICAL CORPORATION (JP) 2016-12-13 US disclosed
US-20150247002-A1 RESIN COMPOSITION, STRETCHED FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2015-09-03 US disclosed
EP-1599167-A2 NOVEL BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AND USE THEREOF AS A MEDICAMENT Société de Conseils de Recherches et d'Applications Scientifiques ( S.C.R.A.S.) (FR) 2005-11-30 EP disclosed
WO-2004075823-A2 NOVEL BENZIMIDAZOLE AND IMIDAZOPYRIDINE DERIVATIVES AND USE THEREOF AS A MEDICAMENT SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) 2004-09-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150247002-A1 RESIN COMPOSITION, STRETCHED FILM, CIRCULARLY POLARIZING PLATE, AND IMAGE DISPLAY DEVICE RAD50, RAD54L, PUF60 HPGD 4343/4885ALDH1A1 3155/4885LPAR1 2101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.