Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MARS2 | Q96GW9 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.31 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.31 |
| ▸ | RPS17 | P08708 | 1/20 | 0.31 |
| ▸ | RPSA | P08865 | 1/20 | 0.31 |
| ▸ | RPS2 | P15880 | 1/20 | 0.31 |
| ▸ | RPL35A | P18077 | 1/20 | 0.31 |
| ▸ | RPL7 | P18124 | 1/20 | 0.31 |
| ▸ | RPL17 | P18621 | 1/20 | 0.31 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.31 |
| ▸ | RPS3 | P23396 | 1/20 | 0.31 |
| ▸ | RPS12 | P25398 | 1/20 | 0.31 |
| ▸ | RPL13 | P26373 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084818 | 0.82 | ALDH1A1 (0.54) | ALDH1A1LMNASMN1; SMN2CYP3A4MARS2 | |
| SCHEMBL5991241 | 0.72 | — | — | |
| SCHEMBL2099402 | 0.70 | KDM4E (0.43) | ALDH1A1LMNATSHRKDM4E | |
| SCHEMBL7279518 | 0.70 | KDM4E (0.43) | ALDH1A1LMNATSHRKDM4E | |
| SCHEMBL1960513 | 0.60 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TSHRNPC1CA12 | |
| SCHEMBL6691324 | 0.59 | ALDH1A1 (0.53) | ALDH1A1CYP3A4TSHRNPC1CA12 | |
| SCHEMBL9137122 | 0.58 | ALDH1A1 (0.51) | ALDH1A1LMNASMN1; SMN2CYP3A4TSHR | |
| SCHEMBL6695879 | 0.57 | ALDH1A1 (0.64) | ALDH1A1MMP2NPC1CA12CA1 | |
| SCHEMBL14749831 | 0.57 | ALDH1A1 (0.39) | ALDH1A1LMNASMN1; SMN2CYP3A4MARS2 | |
| SCHEMBL10999062 | 0.57 | STAT3 (0.35) | ALDH1A1LMNASMN1; SMN2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1580187-A1 | Apoptogenic and antiproliferative analogs of ceramide | Deigner, Hans-Peter (DE) | 2005-09-28 | — | — | EP | claimed |
| EP-1580187-A1 | Apoptogenic and antiproliferative analogs of ceramide | Deigner, Hans-Peter (DE) | 2005-09-28 | — | — | EP | disclosed |