Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | GRM8 | O00222 | 1/20 | 0.49 |
| ▸ | GRM6 | O15303 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18913904 | 0.89 | ALDH1A1 (0.72) | ALDH1A1NPC1GRM8GRM6GRM4 | |
| SCHEMBL1983480 | 0.89 | ALDH1A1 (0.72) | ALDH1A1NPC1GRM8GRM6GRM4 | |
| SCHEMBL240466 | 0.89 | ALDH1A1 (0.72) | ALDH1A1NPC1GRM8GRM6GRM4 | |
| SCHEMBL2368297 | 0.89 | ALDH1A1 (0.72) | ALDH1A1NPC1GRM8GRM6GRM4 | |
| SCHEMBL5106051 | 0.88 | ALDH1A1 (0.54) | ALDH1A1NPC1GRM8GRM6GRM4 | |
| SCHEMBL334438 | 0.85 | ALDH1A1 (0.68) | ALDH1A1NPC1LOXL2MEN1KMT2A | |
| SCHEMBL4942727 | 0.85 | ALDH1A1 (0.68) | ALDH1A1NPC1LOXL2MEN1KMT2A | |
| SCHEMBL7150447 | 0.85 | ALDH1A1 (0.68) | ALDH1A1NPC1LOXL2MEN1KMT2A | |
| SCHEMBL1415694 | 0.84 | ALDH1A1 (0.66) | ALDH1A1NPC1MEN1KMT2AKDM4E | |
| Hydrochloric Acid SCHEMBL26098210 | 0.84 | ALDH1A1 (0.66) | ALDH1A1NPC1LOXL2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040214798-A1 | Nitroaryl phosphoramide compositions and methods for targeting and inhibiting undesirable cell growth or proliferation | HU, LONGQIN | 2004-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040214798-A1 | Nitroaryl phosphoramide compositions and methods for targeting and inhibiting undesirable cell growth or proliferation | MKI67, NME2, NTPCR | ALDH1A1 2164/4885NPC1 685/4885GRM8 4461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.