Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 6/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5153102 | 0.84 | UCHL1 (0.44) | DPP4CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL30343812 | 0.75 | L3MBTL1 (0.39) | CHRNB2CHRNA4L3MBTL1 | |
| SCHEMBL14569588 | 0.75 | DPP4 (0.54) | DPP4GRM5CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL15969593 | 0.73 | CNR1 (0.45) | CNR1 | |
| SCHEMBL15056141 | 0.71 | STK17B (0.39) | GRM5L3MBTL1 | |
| SCHEMBL14557848 | 0.71 | DPP4 (0.51) | DPP4GRM5CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL5151600 | 0.70 | UCHL1 (0.47) | — | |
| SCHEMBL14144107 | 0.69 | POLB (0.45) | L3MBTL1 | |
| SCHEMBL5152841 | 0.69 | DPP4 (0.45) | DPP4CHRNB2CHRNA4 | |
| SCHEMBL30344458 | 0.69 | HPGD (0.38) | P2RY12ESR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1189612-A4 | VLA-4 INHIBITOR COMPOUNDS | DAIICHI SEIYAKU CO (JP) | 2005-02-16 | — | — | EP | disclosed |
| EP-1189612-A1 | VLA-4 INHIBITOR COMPOUNDS | Daiichi Pharmaceutical Co., Ltd. (JP) | 2002-03-27 | — | — | EP | disclosed |
| WO-2001000206-A1 | VLA-4 INHIBITOR COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2001-01-04 | — | — | WO | disclosed |