Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 5/20 | 0.53 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.48 |
| ▸ | MARS1 | P56192 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 5/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.46 |
| ▸ | BCL2 | P10415 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6193095 | 0.87 | RPA1 (0.47) | RPA1MDM2MCL1BCL2 | |
| SCHEMBL6209389 | 0.87 | MDM2 (0.40) | RPA1MALT1MGLLMDM2MCL1 | |
| SCHEMBL6207636 | 0.84 | MGLL (0.57) | RPA1MALT1MARS1CHRNA7MGLL | |
| SCHEMBL5149026 | 0.83 | PTGS2 (0.53) | RPA1CHRNA7 | |
| SCHEMBL5427928 | 0.83 | ALOX5 (0.47) | — | |
| SCHEMBL14505062 | 0.82 | RPA1 (0.56) | RPA1MALT1MARS1CHRNA7MGLL | |
| Hydrochloric Acid SCHEMBL5148901 | 0.82 | RPA1 (0.56) | RPA1MALT1MARS1CHRNA7MDM2 | |
| SCHEMBL5148639 | 0.82 | RPA1 (0.58) | RPA1MALT1MARS1CHRNA7MDM2 | |
| SCHEMBL14505048 | 0.79 | RPA1 (0.57) | RPA1MALT1MARS1CHRNA7MDM2 | |
| SCHEMBL5148778 | 0.78 | CHRNA7 (0.52) | RPA1MALT1MARS1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567503-A1 | PYRAZOLE DERIVATIVES USEFUL AS COX-I INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004050632-A1 | PYRAZOLE DERIVATIVES USEFUL AS COX-I INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-17 | — | — | WO | disclosed |