Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.48 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208715 | 1.00 | PPARG (0.51) | PPARGPPARARAB9ANPC1L3MBTL1 | |
| SCHEMBL10798007 | 0.81 | NPC1 (0.70) | PPARGPPARARAB9ANPC1L3MBTL1 | |
| SCHEMBL3080187 | 0.81 | NPC1 (0.70) | PPARGPPARARAB9ANPC1L3MBTL1 | |
| SCHEMBL3080186 | 0.81 | NPC1 (0.70) | PPARGPPARARAB9ANPC1L3MBTL1 | |
| SCHEMBL14353303 | 0.80 | ALDH1A1 (0.53) | L3MBTL1SMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL13351487 | 0.80 | ALDH1A1 (0.53) | L3MBTL1SMN1; SMN2GAAALDH1A1KDM4E | |
| SCHEMBL6873224 | 0.79 | G6PC1 (0.56) | PPARGPPARARAB9ANPC1L3MBTL1 | |
| SCHEMBL8109795 | 0.79 | SMN1; SMN2 (0.64) | PPARGPPARARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28114466 | 0.79 | KMT2A (0.60) | PPARGPPARARAB9ANPC1L3MBTL1 | |
| SCHEMBL8109792 | 0.79 | SMN1; SMN2 (0.64) | PPARGPPARARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130004979-A1 | GLYCOSYLTRANSFERASE REVERSIBILITY FOR SUGAR NUCLEOTIDE SYNTHESIS AND MICROSCALE SCANNING | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-01-03 | — | — | US | disclosed |
| US-20130004979-A1 | GLYCOSYLTRANSFERASE REVERSIBILITY FOR SUGAR NUCLEOTIDE SYNTHESIS AND MICROSCALE SCANNING | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-01-03 | — | — | US | disclosed |
| US-20130004979-A1 | GLYCOSYLTRANSFERASE REVERSIBILITY FOR SUGAR NUCLEOTIDE SYNTHESIS AND MICROSCALE SCANNING | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-01-03 | — | — | US | disclosed |
| EP-1503988-A2 | FREDERICAMYCIN DERIVATIVES | Biofrontera Discovery Gmbh (DE) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003080582-A2 | FREDERICAMYCIN DERIVATIVES | BIOFRONTERA DISCOVERY GMBH (DE) | 2003-10-02 | — | — | WO | disclosed |