Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA3 | P15088 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 4/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6208734 | 1.00 | CPA3 (0.50) | CPA3FOLH1MMELTA4HTSHR | |
| SCHEMBL6209579 | 0.83 | CPA3 (0.47) | CPA3FOLH1MMELTA4H | |
| SCHEMBL6209574 | 0.83 | CPA3 (0.47) | CPA3FOLH1MMELTA4H | |
| SCHEMBL6208838 | 0.79 | CPA3 (0.48) | CPA3FOLH1MMELTA4HTSHR | |
| SCHEMBL6208840 | 0.79 | CPA3 (0.48) | CPA3FOLH1MMELTA4HTSHR | |
| SCHEMBL7333784 | 0.78 | CPA3 (0.52) | CPA3FOLH1MMELTA4H | |
| SCHEMBL7315467 | 0.78 | CPA3 (0.52) | CPA3FOLH1MMELTA4H | |
| SCHEMBL7313773 | 0.78 | CPA3 (0.52) | CPA3FOLH1MMELTA4H | |
| SCHEMBL7323948 | 0.78 | CPA3 (0.52) | CPA3FOLH1MMELTA4H | |
| SCHEMBL6209106 | 0.77 | CPA3 (0.51) | CPA3FOLH1MMELTA4HCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0883612-B1 | THIOL DERIVATIVES WITH METALLOPEPTIDASE (ACE/NEP) INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 2005-02-23 | — | — | EP | claimed |
| EP-0883612-B1 | THIOL DERIVATIVES WITH METALLOPEPTIDASE (ACE/NEP) INHIBITORY ACTIVITY | ZAMBON SPA (IT) | 2005-02-23 | — | — | EP | disclosed |
| US-6166051-A | Thiol derivatives with metallopeptidase (ACE/NEP) inhibitory activity | ZAMBON GROUP S.P.A. (IT) | 2000-12-26 | — | — | US | disclosed |
| EP-0883612-A1 | THIOL DERIVATIVES WITH METALLOPEPTIDASE (ACE/NEP) INHIBITORY ACTIVITY | ZAMBON GROUP S.p.A. (IT) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997024341-A1 | THIOL DERIVATIVES WITH METALLOPEPTIDASE (ACE/NEP) INHIBITORY ACTIVITY | ZAMBON GROUP S.P.A. (IT) | 1997-07-10 | — | — | WO | disclosed |