Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213790 | 0.75 | P2RX4 (0.33) | P2RX4MAPTSMN1; SMN2 | |
| SCHEMBL9429035 | 0.70 | TRPA1 (0.31) | — | |
| SCHEMBL5637462 | 0.67 | TRPA1 (0.31) | MAPT | |
| SCHEMBL6272460 | 0.67 | ALDH1A1 (0.32) | MEN1KMT2ABCHE | |
| SCHEMBL8210685 | 0.67 | LMNA (0.34) | NPC1RAB9ABCHE | |
| SCHEMBL28445790 | 0.66 | TRPA1 (0.31) | — | |
| SCHEMBL27996262 | 0.66 | TRPA1 (0.32) | — | |
| SCHEMBL11569287 | 0.65 | — | — | |
| Acetic Acid SCHEMBL11657200 | 0.64 | NOX1 (0.47) | P2RX4MEN1KMT2ABCHEMAPT | |
| Carbamic Acid SCHEMBL4912022 | 0.62 | LMNA (0.36) | P2RX4BCHEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554250-A1 | NOVEL LACTAMS AND USES THEREOF | AstraZeneca AB (SE) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004031154-A1 | NOVEL LACTAMS AND USES THEREOF | ASTRAZENECA AB (SE) | 2004-04-15 | — | — | WO | disclosed |