Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 14/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29196216 | 0.92 | GRM5 (0.67) | GRM5MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL20165273 | 0.83 | GRM5 (0.54) | GRM5MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL31279913 | 0.80 | MAOB (0.52) | GRM5MAOBMAOAALDH1A1NPC1 | |
| SCHEMBL10334859 | 0.80 | MAOB (0.52) | GRM5MAOBMAOAALDH1A1NPC1 | |
| SCHEMBL27762425 | 0.77 | GRM5 (0.67) | GRM5MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL6628767 | 0.77 | MAOA (0.54) | MEN1KMT2AMAOBMAOA | |
| SCHEMBL21081795 | 0.76 | GRM5 (0.42) | GRM5MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL6365078 | 0.76 | GRM5 (0.56) | GRM5MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL29177251 | 0.76 | MEN1 (0.47) | GRM5MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7605647 | 0.76 | GRM5 (0.49) | GRM5MAPTMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594495-A1 | OXAZOLIDINONE DERIVATES N-SUBSTITUTED BY A TRICYCLIC RING, FOR USE AS ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2005-11-16 | — | — | EP | disclosed |
| WO-2004069245-A1 | OXAZOLIDINONE DERIVATES N-SUBSTITUTED BY A TRICYCLIC RING, FOR USE AS ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2004-08-19 | — | — | WO | disclosed |