Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 16/20 | 0.54 |
| ▸ | MAOB | P27338 | 16/20 | 0.54 |
| ▸ | PRKCI | P41743 | 1/20 | 0.54 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.49 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319226 | 0.84 | BAZ2B (0.56) | MAOAMAOBPRKCIBAZ2BHSD17B1 | |
| SCHEMBL17996957 | 0.82 | BAZ2B (0.57) | MAOAMAOBPRKCIBAZ2BHSD17B1 | |
| SCHEMBL5485052 | 0.82 | SMN1; SMN2 (0.55) | MEN1KMT2A | |
| SCHEMBL9403386 | 0.81 | MAOA (0.53) | MAOAMAOBPRKCIBAZ2B | |
| SCHEMBL11727398 | 0.81 | MAOB (0.53) | MAOAMAOBPRKCIBAZ2BHSD17B1 | |
| SCHEMBL29042317 | 0.81 | MAPT (0.46) | MEN1KMT2A | |
| SCHEMBL11735810 | 0.81 | MAOA (0.54) | MAOAMAOBPRKCIBAZ2BHSD17B1 | |
| SCHEMBL29042298 | 0.81 | MAPT (0.46) | MEN1KMT2A | |
| SCHEMBL11746728 | 0.80 | MAOA (0.57) | MAOAMAOBPRKCIHSD17B1MEN1 | |
| SCHEMBL390556 | 0.80 | PARP10 (0.53) | MAOAMAOBPRKCIBAZ2BHSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116490201-A | Inhibitors of YAP/TAZ-TEAD tumor proteins, their synthesis and use | 布里奇恩生物科学公司 | 2023-07-25 | — | — | CN | disclosed |
| EP-1458375-A2 | COMPOSITIONS FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| EP-1458374-A2 | COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003051841-A2 | COMPOUNDS AND USES THEREOF FOR DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |
| WO-2003051842-A2 | COMPOSITIONS DECREASING ACTIVITY OF HORMONE-SENSITIVE LIPASE | NOVO NORDISK A/S (DK) | 2003-06-26 | — | — | WO | disclosed |