Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.34 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.34 |
| ▸ | ITGAL | P20701 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | ACE | P12821 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.31 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10642674 | 0.86 | TP53 (0.62) | TP53L3MBTL1FOLH1ITGB3ITGB2 | |
| SCHEMBL7414681 | 0.86 | TP53 (0.62) | TP53L3MBTL1FOLH1ITGB3ITGB2 | |
| SCHEMBL10642729 | 0.77 | TP53 (0.56) | TP53L3MBTL1FOLH1ITGB3ITGB2 | |
| SCHEMBL10639478 | 0.76 | FOLH1 (0.53) | TP53L3MBTL1FOLH1ITGB3ITGB2 | |
| SCHEMBL3608667 | 0.74 | TP53 (0.51) | TP53L3MBTL1FOLH1ITGB3ITGB2 | |
| SCHEMBL3604862 | 0.74 | TP53 (0.51) | TP53L3MBTL1FOLH1ITGB3ITGB2 | |
| SCHEMBL3587342 | 0.74 | TP53 (0.51) | TP53L3MBTL1FOLH1ITGB3ITGB2 | |
| SCHEMBL3593228 | 0.74 | L3MBTL1 (0.63) | TP53L3MBTL1ALDH1A1MAPTTDP1 | |
| SCHEMBL3607831 | 0.73 | TP53 (0.50) | TP53L3MBTL1FOLH1ITGB3ITGB2 | |
| SCHEMBL17964289 | 0.73 | TP53 (0.50) | TP53L3MBTL1FOLH1ITGB3ITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608662-A1 | GUANIDINE DERIVATIVES AND USE THEREOF AS NEUROPEPTIDE FF RECEPTOR ANTAGONISTS | Actelion Pharmaceuticals Ltd. (CH) | 2005-12-28 | — | — | EP | disclosed |
| WO-2004083218-A1 | GUANIDINE DERIVATIVES AND USE THEREOF AS NEUROPEPTIDE FF RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2004-09-30 | — | — | WO | disclosed |