Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | NNMT | P40261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10952238 | 0.77 | RAB9A (0.46) | ALDH1A1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL10958010 | 0.77 | CYP1A2 (0.50) | LMNAALDH1A1CYP2A6SMN1; SMN2RAB9A | |
| Bromide SCHEMBL6282386 | 0.76 | RAB9A (0.45) | ALDH1A1SMN1; SMN2RAB9AKDM4E | |
| SCHEMBL3229246 | 0.75 | NFE2L2 (0.53) | MAPTALDH1A1CYP2A6SMN1; SMN2MAPK1 | |
| SCHEMBL1694647 | 0.72 | BACE1 (0.51) | LMNAALDH1A1HTTSMN1; SMN2RAB9A | |
| SCHEMBL3816388 | 0.71 | NNMT (0.48) | MAPTLMNANNMTALDH1A1CYP2A6 | |
| SCHEMBL29525223 | 0.71 | NNMT (0.48) | MAPTLMNANNMTALDH1A1CYP2A6 | |
| SCHEMBL77481 | 0.70 | KDM4E (0.47) | MAPTNNMTCYP2A6SMN1; SMN2RAB9A | |
| SCHEMBL22079377 | 0.70 | NNMT (0.48) | MAPTLMNANNMTALDH1A1CYP2A6 | |
| SCHEMBL13009068 | 0.69 | RAB9A (0.64) | MAPTLMNALIPEALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583749-A1 | OXAZOLE DERIVATIVES AS INHIBITORS OF CYCLOOXYGENASE | Astellas Pharma Inc. (JP) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004065374-A1 | OXAZOLE DERIVATIVES AS INHIBITORS OF CYCLOOXYGENASE | ASTELLAS PHARMA INC. (JP) | 2004-08-05 | — | — | WO | disclosed |