Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3707221 | 0.89 | CALM1 (0.39) | ALDH1A1HPGDEPHX1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11549616 | 0.88 | CALM1 (0.38) | ALDH1A1HPGDEPHX1KMT2AMEN1 | |
| SCHEMBL1399903 | 0.83 | ALDH1A1 (0.50) | ALDH1A1HPGDEPHX1KMT2AMEN1 | |
| SCHEMBL8414683 | 0.82 | CALM1 (0.39) | ALDH1A1HPGDEPHX1KMT2AMEN1 | |
| SCHEMBL112394 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HPGDEPHX1KMT2AMEN1 | |
| SCHEMBL6806443 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HPGDEPHX1KMT2AMEN1 | |
| SCHEMBL8206338 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HPGDEPHX1KMT2AMEN1 | |
| SCHEMBL111084 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HPGDEPHX1KMT2AMEN1 | |
| SCHEMBL2333440 | 0.81 | CALM1 (0.46) | ALDH1A1HPGDEPHX1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL3407515 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HPGDEPHX1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450784-A4 | HSP90-INHIBITING ZEARALANOL COMPOUNDS AND METHODS OF PRODUCING AND USING SAME | CONFORMA THERAPEUTICS CORP (US) | 2005-02-09 | — | — | EP | disclosed |
| EP-1450784-A2 | HSP90-INHIBITING ZEARALANOL COMPOUNDS AND METHODS OF PRODUCING AND USING SAME | Conforma Therapeutics Corporation (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003041643-A2 | HSP90-INHIBITING ZEARALANOL COMPOUNDS AND METHODS OF PRODUCING AND USING SAME | CONFORMA THERAPEUTICS CORPORATION (US) | 2003-05-22 | — | — | WO | disclosed |