SCHEMBL620975

SCHEMBL620975

CCC(C)(C)C[CH]CC(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4294983 0.80 TSHR (0.36) TSHRTDP1
SCHEMBL4618318 0.79
SCHEMBL1341716 0.78
SCHEMBL27403877 0.74 TSHR (0.30) TSHRTDP1
SCHEMBL28018986 0.74
SCHEMBL306915 0.74
SCHEMBL3030245 0.71
SCHEMBL27976951 0.71 TSHR (0.35) TSHR
SCHEMBL28018092 0.71 TSHR (0.35) TSHR
SCHEMBL27976617 0.71 TSHR (0.35) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150368380-A1 ANTIMICROBIAL POLYMER Fachhochschule Münster (DE) 2015-12-24 US claimed
US-10138307-B2 Antimicrobial polymer Fachhochschule Münster (DE) 2018-11-27 US disclosed
CN-104955926-B For improving the lubricant compositions for including epoxide compound of fluoropolymer sealant compatibility 巴斯夫欧洲公司 2018-06-22 CN disclosed
CN-105247025-B Seal compatibility additives for lubricant compositions for improving fluoropolymer seal compatibility 巴斯夫欧洲公司 2017-12-01 CN disclosed
CN-107109278-A For the sulphonic acid ester for the fluoropolymer seal part compatibility for improving lubricant compositions 巴斯夫欧洲公司 2017-08-29 CN disclosed
CN-104822810-B Comprising boroxin and amines to improve the lubricant compositions of fluoropolymer seal part compatibility 巴斯夫欧洲公司 2017-03-08 CN disclosed
EP-2976087-A1 ROR GAMMA MODULATORS ETH Zürich (CH) 2016-01-27 EP disclosed
CN-105283529-A Seal compatibility additives for lubricant compositions for improving fluoropolymer seal compatibility BASF SE 2016-01-27 CN disclosed
CN-105247025-A Seal compatibility additives for lubricant compositions for improving fluoropolymer seal compatibility BASF SE 2016-01-13 CN disclosed
CN-105247024-A Seal compatibility additives for lubricant compositions for improving fluoropolymer seal compatibility BASF SE 2016-01-13 CN disclosed
US-7842706-B2 Pharmaceutical composition TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2010-11-30 US disclosed
US-20090246232-A1 Pharmaceutical composition TAKEDA PHARMACEUTICAL COMPANY, LIMITED 2009-10-01 US disclosed
CN-101522813-A Resin composition and molded article obtained from the composition MITSUI CHEMICALS INC (JP) 2009-09-02 CN disclosed
US-7538125-B2 Pharmaceutical composition TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-05-26 US disclosed
US-20070203198-A1 Pharmaceutical composition TAKEDA PHARMACEUTICAL COMPANY LIMITED 2007-08-30 US disclosed
US-7144900-B2 Insulin sensitivity enhancer such as 5 -[[4-[2-(methyl-2-pyridylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione or salt and a statin; antidiabetic agent TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2006-12-05 US disclosed
US-20050054685-A1 Pharmaceutical composition TAKEDA CHEMICAL INDUSTRIES, LTD. 2005-03-10 US disclosed
EP-0779281-B1 ISOXAZOLES SANKYO CO (JP) 2003-10-29 EP disclosed
US-5965591-A MONOAMINE OXIDASE INHIBITOR; FOR PROPHYLAXIS AND TREATING PARKINSON'S DISEASE, DEPRESSION AND ALZHEIMER'S DISEASE SANKYO COMPANY, LIMITED (JP) 1999-10-12 US disclosed
EP-0779281-A1 ISOXAZOLES SANKYO COMPANY LIMITED (JP) 1997-06-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10138307-B2 Antimicrobial polymer PUF60, PARG, DPM1 TSHR 4853/4885TDP1 3198/4885
US-20050054685-A1 Pharmaceutical composition GPR119, IAPP, INSR TSHR 1868/4885TDP1 2516/4885
US-20070203198-A1 Pharmaceutical composition GPR119, IAPP, INSR TSHR 1868/4885TDP1 2516/4885
US-20090246232-A1 Pharmaceutical composition GPR119, IAPP, INSR TSHR 1868/4885TDP1 2516/4885
US-20150368380-A1 ANTIMICROBIAL POLYMER PUF60, PARG, DPM1 TSHR 4853/4885TDP1 3198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.