Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 13/20 | 0.41 |
| ▸ | CTSK | P43235 | 13/20 | 0.41 |
| ▸ | CTSS | P25774 | 12/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CTSV | O60911 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6213978 | 0.94 | CASR (0.38) | CTSLCTSKCTSSCASRCTSV | |
| SCHEMBL6211873 | 0.94 | CTSK (0.39) | CTSLCTSKCTSSCASR | |
| SCHEMBL6211275 | 0.92 | ITGB3 (0.38) | CTSLCTSKCTSSCASR | |
| SCHEMBL6210259 | 0.90 | MEN1 (0.38) | CTSLCTSKCTSSKMT2ACTSV | |
| SCHEMBL6212649 | 0.90 | NPC1 (0.40) | NPC1HPGDSCASRKMT2A | |
| SCHEMBL6211016 | 0.89 | CTSK (0.37) | CTSLCTSKCTSSCTSVCTSB | |
| SCHEMBL6213254 | 0.89 | CTSK (0.44) | CTSLCTSKCTSSKMT2ACTSV | |
| SCHEMBL6210934 | 0.88 | CTSK (0.44) | CTSLCTSKCTSSCTSVCTSB | |
| SCHEMBL6211626 | 0.88 | CCR5 (0.38) | CTSLCTSKCTSS | |
| SCHEMBL6210002 | 0.87 | CTSK (0.36) | CTSLCTSKCTSSCTSVCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |