Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2135868 | 0.84 | PNMT (0.32) | PNMT | |
| Hydrochloric Acid SCHEMBL9066343 | 0.84 | PNMT (0.32) | PNMT | |
| Hydrochloric Acid SCHEMBL5688812 | 0.84 | NPC1 (0.34) | PNMT | |
| Fluoride Ion SCHEMBL3470296 | 0.82 | PNMT (0.32) | PNMT | |
| Hydrochloric Acid SCHEMBL8676755 | 0.80 | PNMT (0.35) | PNMT | |
| SCHEMBL28119166 | 0.78 | PNMT (0.36) | PNMT | |
| SCHEMBL6211217 | 0.78 | PNMT (0.33) | PNMT | |
| Hydrochloric Acid SCHEMBL618232 | 0.77 | PNMT (0.33) | PNMT | |
| Hydrochloric Acid SCHEMBL3693755 | 0.76 | PNMT (0.33) | PNMT | |
| SCHEMBL9280866 | 0.74 | PNMT (0.33) | PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848022-B1 | Production of Ethylene/Butene copolymers with a single metallocene catalyst and a single monomer | TOTAL PETROCHEMICALS RES FELUY (BE) | 2005-03-02 | — | — | EP | claimed |
| EP-0848022-A1 | Production of Ethylene/Butene copolymers with a single metallocene catalyst and a single monomer | FINA TECHNOLOGY, INC. (US) | 1998-06-17 | — | — | EP | claimed |
| EP-0848022-B1 | Production of Ethylene/Butene copolymers with a single metallocene catalyst and a single monomer | TOTAL PETROCHEMICALS RES FELUY (BE) | 2005-03-02 | — | — | EP | disclosed |
| EP-0848022-A1 | Production of Ethylene/Butene copolymers with a single metallocene catalyst and a single monomer | FINA TECHNOLOGY, INC. (US) | 1998-06-17 | — | — | EP | disclosed |