Hydrochloric Acid

Hydrochloric Acid

SCHEMBL618232

C[Si](C)=[Zr+2]c1c(C2=CC=CC2)ccc2c1Cc1ccccc1-2.[Cl-].[Cl-]

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.33
DRD2 P14416 1/20 0.32
DRD4 P21917 1/20 0.32
DRD3 P35462 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
PGR P06401 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9083565 0.84 PNMT (0.34) PNMTDRD2DRD4DRD3NPC1
Hydrochloric Acid SCHEMBL3894866 0.82 PNMT (0.33) PNMTDRD2DRD4DRD3NPC1
Hydrochloric Acid SCHEMBL617844 0.82 NPC1 (0.37) PNMTDRD2DRD4DRD3NPC1
Hydrochloric Acid SCHEMBL944866 0.82 PNMT (0.33) PNMTDRD2DRD4DRD3NPC1
SCHEMBL6522771 0.80 NPC1 (0.37) PNMTDRD2DRD4DRD3NPC1
Fluoride Ion SCHEMBL3469916 0.80 NPC1 (0.37) PNMTDRD2DRD4DRD3NPC1
Hydrochloric Acid SCHEMBL7772246 0.79 PNMT (0.31) PNMTDRD2DRD4DRD3NPC1
Hydrochloric Acid SCHEMBL5086526 0.79 SRD5A2 (0.35) PNMTDRD2DRD4DRD3NPC1
SCHEMBL28762096 0.78 PNMT (0.37) PNMTDRD2DRD4DRD3NPC1
Hydrochloric Acid SCHEMBL27425148 0.78 PNMT (0.42) PNMTDRD2DRD4DRD3NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240228682-A1 POLYETHYLENE COPOLYMER WITH BROAD SHORT CHAIN BRANCHING DISTRIBUTION W.R. GRACE & CO.-CONN. (US) 2024-07-11 US disclosed
EP-4337703-A1 POLYETHYLENE COPOLYMER WITH BROAD SHORT CHAIN BRANCHING DISTRIBUTION W. R. Grace & Co.-Conn (US) 2024-03-20 EP disclosed
EP-2683749-B1 ALUMINOXANE CATALYST ACTIVATORS CONTAINING CARBOCATION AGENTS, AND USE THEREOF IN POLYOLEFIN CATALYSTS GRACE W R & CO (US) 2023-06-07 EP disclosed
WO-2022241225-A1 POLYETHYLENE COPOLYMER WITH BROAD SHORT CHAIN BRANCHING DISTRIBUTION W.R. GRACE & CO.-CONN. (US) 2022-11-17 WO disclosed
US-10870715-B2 Solid polyaluminoxane composition, olefin polymerization catalyst, olefin polymer production method and solid polyaluminoxane composition production method MITSUI CHEMICALS, INC. (JP) 2020-12-22 US disclosed
EP-3312200-B1 SOLID POLYALUMINOXANE COMPOSITION, OLEFIN POLYMERIZATION CATALYST, OLEFIN POLYMER PRODUCTION METHOD AND SOLID POLYALUMINOXANE COMPOSITION PRODUCTION METHOD MITSUI CHEMICALS INC (JP) 2019-06-19 EP disclosed
US-10150823-B2 Solid polyaluminoxane composition, olefin polymerization catalyst, olefin polymer production method and solid polyaluminoxane composition production method MITSUI CHEMICALS, INC. (JP) 2018-12-11 US disclosed
EP-3312200-A1 SOLID POLYALUMINOXANE COMPOSITION, OLEFIN POLYMERIZATION CATALYST, OLEFIN POLYMER PRODUCTION METHOD AND SOLID POLYALUMINOXANE COMPOSITION PRODUCTION METHOD Mitsui Chemicals, Inc. (JP) 2018-04-25 EP disclosed
EP-2955187-B1 SOLID POLYALUMINOXANE COMPOSITION, CATALYST FOR OLEFIN POLYMERIZATION AND METHOD FOR PRODUCING OLEFIN POLYMER MITSUI CHEMICALS INC (JP) 2018-01-31 EP disclosed
US-20170240664-A1 SOLID POLYALUMINOXANE COMPOSITION, OLEFIN POLYMERIZATION CATALYST, OLEFIN POLYMER PRODUCTION METHOD AND SOLID POLYALUMINOXANE COMPOSITION PRODUCTION METHOD MITSUI CHEMICALS, INC. (JP) 2017-08-24 US disclosed
US-5296565-A Polymerizing olefins using catalyst comprising particulate oxide carrier, organoaluminum oxy compound, metallocene, organoaluminum compound, prepolymerized polyolefin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-03-22 US disclosed
US-5292845-A Ethylene/alpha-olefin/7-methyl-1,6-octadiene copolymer rubber and composition of the same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-03-08 US disclosed
EP-0582480-A2 Olefin polymerization catalyst and method for the polymerization of olefin using said polymerization catalyst MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1994-02-09 EP disclosed
US-5252529-A Coordination catalyst using a moisture-adsorbed carrier of a metal oxide; addition polymers having excellent melt tension and moldability and broad molecular weight distribution MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-10-12 US disclosed
EP-0552946-A1 Ethylene/alpha-olefin/7-methyl-1,6-octadiene copolymer rubber and composition of the same MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-07-28 EP disclosed
EP-0552945-A2 Process for the preparation of polyolefin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-07-28 EP disclosed
EP-0536503-A2 Olefin polymer composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-04-14 EP disclosed
EP-0534119-A2 Prepolymerized olefin polymerization catalyst and olefin polymerization process MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-03-31 EP disclosed
EP-0516458-A2 Olefin polymerization solid catalyst, olefin polymerization catalyst and olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-12-02 EP disclosed
EP-0515132-A2 Olefin polymerization catalyst and olefin polymerization MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-11-25 EP disclosed