Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 14/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 13/20 | 0.36 |
| ▸ | CTSS | P25774 | 12/20 | 0.36 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.35 |
| ▸ | CTSV | O60911 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210934 | 0.94 | CTSK (0.44) | CTSKGAACTSLCTSSCTSV | |
| SCHEMBL6210259 | 0.91 | MEN1 (0.38) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL6211016 | 0.91 | CTSK (0.37) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL6213254 | 0.90 | CTSK (0.44) | CTSKALDH1A1CTSLCTSSCTSV | |
| SCHEMBL6211626 | 0.89 | CCR5 (0.38) | CTSKCTSLCTSS | |
| SCHEMBL6211360 | 0.89 | CHRM4 (0.40) | CTSKALDH1A1GAACTSLCTSS | |
| SCHEMBL6213978 | 0.89 | CASR (0.38) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL6210002 | 0.89 | CTSK (0.36) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL6211873 | 0.88 | CTSK (0.39) | CTSKCTSLCTSS | |
| SCHEMBL6209035 | 0.88 | CTSK (0.36) | CTSKALDH1A1SMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |