Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | ESRRG | P62508 | 2/20 | 0.34 |
| ▸ | ESRRB | O95718 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | NAMPT | P43490 | 3/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210227 | 0.90 | LMNA (0.35) | CTSKSMN1; SMN2LMNAHTTNAMPT | |
| SCHEMBL6210476 | 0.88 | CTSK (0.36) | CTSKSMN1; SMN2LMNAHTTATM | |
| SCHEMBL6209898 | 0.88 | CTSK (0.38) | CTSKALDH1A1SMYD3 | |
| SCHEMBL6210187 | 0.87 | CTSK (0.40) | CTSK | |
| SCHEMBL6210912 | 0.86 | ITGB3 (0.37) | CTSKSMN1; SMN2LMNAHTTATM | |
| SCHEMBL6209104 | 0.85 | CHRM4 (0.41) | SMN1; SMN2LMNAHTTKMT2AMEN1 | |
| SCHEMBL6210748 | 0.85 | CTSK (0.49) | CTSKSMN1; SMN2LMNAHTTNAMPT | |
| SCHEMBL6213162 | 0.85 | CTSK (0.42) | CTSKSMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL6212272 | 0.82 | CTSK (0.46) | CTSKNAMPTALDH1A1KMT2APOLB | |
| SCHEMBL6210710 | 0.82 | CTSK (0.38) | CTSKSMN1; SMN2LMNAALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |