Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 14/20 | 0.44 |
| ▸ | CTSL | P07711 | 14/20 | 0.44 |
| ▸ | CTSS | P25774 | 10/20 | 0.44 |
| ▸ | CTSB | P07858 | 4/20 | 0.44 |
| ▸ | CTSV | O60911 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046863 | 0.90 | SMYD3 (0.35) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6209230 | 0.88 | CCR1 (0.45) | CTSK | |
| SCHEMBL6211183 | 0.86 | CTSK (0.42) | CTSKCTSLCTSSCTSBCHRNB2 | |
| SCHEMBL6242644 | 0.85 | CTSK (0.60) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL4040649 | 0.85 | CTSK (0.42) | CTSK | |
| SCHEMBL4047844 | 0.84 | SMYD3 (0.35) | CTSK | |
| SCHEMBL4045831 | 0.83 | CTSK (0.51) | CTSKCTSS | |
| SCHEMBL4041827 | 0.83 | CTSK (0.43) | CTSK | |
| SCHEMBL4039411 | 0.83 | CTSK (0.43) | CTSK | |
| SCHEMBL4042752 | 0.83 | CTSK (0.52) | CTSKCHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | claimed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | claimed |