Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.72 |
| ▸ | FABP4 | P15090 | 1/20 | 0.72 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.72 |
| ▸ | CDK2 | P24941 | 1/20 | 0.72 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.72 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.70 |
| ▸ | SNCA | P37840 | 2/20 | 0.52 |
| ▸ | CD40 | P25942 | 3/20 | 0.49 |
| ▸ | CD40LG | P29965 | 3/20 | 0.49 |
| ▸ | CHAT | P28329 | 1/20 | 0.49 |
| ▸ | FABP1 | P07148 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | UQCRB | P14927 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210121 | 0.88 | MAPK14 (0.66) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL6214268 | 0.86 | TTR (0.76) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL43158 | 0.84 | FABP4 (1.00) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL29381891 | 0.84 | FABP4 (1.00) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL6654772 | 0.82 | FABP4 (0.97) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL1786500 | 0.82 | FABP4 (0.97) | TTRFABP4CCNA2CDK2MAPK14 | |
| Ammonia Solution, Strong SCHEMBL592279 | 0.82 | NR4A1 (1.00) | TTRFABP4CCNA2CDK2MAPK14 | |
| Ammonia Solution, Strong SCHEMBL592280 | 0.82 | NR4A1 (1.00) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL10353163 | 0.82 | FABP4 (0.97) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL11056657 | 0.82 | TTR (0.70) | TTRFABP4CCNA2CDK2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224240-B1 | 8-(ANILINO)-1-NAPHTHALENESULFONATE ANALOGS AND THEIR USE IN ANALYTE DETECTION ASSAYS | LIFESCAN INC (US) | 2005-02-23 | — | — | EP | claimed |
| EP-1510555-A1 | 8-(anilino)-1-naphthalenesulfonate analogs and their use in analyte detection assays | Lifescan, Inc. (US) | 2005-03-02 | — | — | EP | disclosed |
| EP-1224240-B1 | 8-(ANILINO)-1-NAPHTHALENESULFONATE ANALOGS AND THEIR USE IN ANALYTE DETECTION ASSAYS | LIFESCAN INC (US) | 2005-02-23 | — | — | EP | disclosed |
| CN-1413235-A | 8- (anilino) -1-naphthalenesulfonate analogs and their use in analyte detection assays | LIFESCAN INC (US) | 2003-04-23 | — | — | CN | disclosed |
| EP-1224240-A1 | 8-(ANILINO)-1-NAPHTHALENESULFONATE ANALOGS AND THEIR USE IN ANALYTE DETECTION ASSAYS | Lifescan, Inc. (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001030915-A1 | 8-(ANILINO)-1-NAPHTHALENESULFONATE ANALOGS AND THEIR USE IN ANALYTE DETECTION ASSAYS | LIFESCAN, INC. (US) | 2001-05-03 | — | — | WO | disclosed |
| US-6218571-B1 | COUPLING WITH 3-METHYL-2-BENZOTHIAZOLINONE HYDRAZONE HYDROCHLORIDE TO MAKE DYE; REDUCED DRIFT; GLUCOSE DETECTION IN BLOOD | LIFESCAN, INC. | 2001-04-17 | — | — | US | disclosed |