Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 16/20 | 0.48 |
| ▸ | NQO2 | P16083 | 2/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6194688 | 0.88 | MTNR1A (0.50) | MTNR1AMTNR1BNQO2TACR1 | |
| SCHEMBL5094791 | 0.88 | TACR1 (0.43) | MTNR1AMTNR1BTACR1 | |
| SCHEMBL6193835 | 0.83 | MTNR1A (0.66) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL4430575 | 0.81 | MTNR1A (0.72) | MTNR1AMTNR1B | |
| SCHEMBL6211450 | 0.77 | TACR1 (0.36) | MTNR1AMTNR1BTACR1 | |
| SCHEMBL5089786 | 0.76 | TACR1 (0.43) | MTNR1AMTNR1BTACR1 | |
| SCHEMBL6193264 | 0.74 | MTNR1A (0.46) | MTNR1AMTNR1BNQO2TACR1 | |
| SCHEMBL5094795 | 0.72 | CTSG (0.35) | TACR1 | |
| SCHEMBL6193804 | 0.69 | MTNR1A (0.44) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL4437298 | 0.69 | MTNR1A (0.72) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517909-A2 | NOVEL TETRACYCLIC ARYLCARBONYL INDOLES HAVING SEROTONIN RECEPTOR AFFINITY USEFUL AS THERAPEUTIC AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Suven Life Sciences Limited (IN) | 2005-03-30 | — | — | EP | claimed |
| WO-2004000205-A2 | NOVEL TETRACYCLIC ARYLCARBONYL INDOLES HAVING SEROTONIN RECEPTOR AFFINITY USEFUL AS THERAPEUTIC AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2003-12-31 | — | — | WO | claimed |