Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 14/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5101221 | 0.90 | TACR1 (0.36) | MTNR1AMTNR1BRXRATACR1 | |
| SCHEMBL6194688 | 0.82 | MTNR1A (0.50) | MTNR1AMTNR1BTACR1NQO2 | |
| SCHEMBL4426344 | 0.82 | MTNR1A (0.68) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL6193835 | 0.77 | MTNR1A (0.66) | MTNR1AMTNR1BNQO2ALDH1A1 | |
| SCHEMBL5820446 | 0.75 | MAPT (0.33) | ALDH1A1 | |
| SCHEMBL6211448 | 0.74 | MTNR1A (0.48) | MTNR1AMTNR1BTACR1NQO2 | |
| SCHEMBL6193804 | 0.73 | MTNR1A (0.44) | MTNR1AMTNR1BGFERNQO2ALDH1A1 | |
| SCHEMBL3254021 | 0.71 | MTNR1A (0.53) | MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL5089786 | 0.69 | TACR1 (0.43) | MTNR1AMTNR1BTACR1ALDH1A1 | |
| SCHEMBL28888717 | 0.65 | MAT2A (0.41) | MTNR1AMTNR1BTACR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517909-A2 | NOVEL TETRACYCLIC ARYLCARBONYL INDOLES HAVING SEROTONIN RECEPTOR AFFINITY USEFUL AS THERAPEUTIC AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Suven Life Sciences Limited (IN) | 2005-03-30 | — | — | EP | claimed |
| WO-2004000205-A2 | NOVEL TETRACYCLIC ARYLCARBONYL INDOLES HAVING SEROTONIN RECEPTOR AFFINITY USEFUL AS THERAPEUTIC AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2003-12-31 | — | — | WO | claimed |
| EP-1517909-A2 | NOVEL TETRACYCLIC ARYLCARBONYL INDOLES HAVING SEROTONIN RECEPTOR AFFINITY USEFUL AS THERAPEUTIC AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Suven Life Sciences Limited (IN) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000205-A2 | NOVEL TETRACYCLIC ARYLCARBONYL INDOLES HAVING SEROTONIN RECEPTOR AFFINITY USEFUL AS THERAPEUTIC AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SUVEN LIFE SCIENCES LIMITED (IN) | 2003-12-31 | — | — | WO | disclosed |