Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.32 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6215709 | 0.99 | KMT2A (0.40) | KMT2ATHRBKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL6214878 | 0.90 | KMT2A (0.54) | KMT2ATHRBKDM4EMEN1LMNA | |
| SCHEMBL6216347 | 0.87 | KDM4E (0.43) | KMT2ATHRBKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL6217020 | 0.86 | CYP2C19 (0.42) | KMT2ASMN1; SMN2MEN1CYP2C19L3MBTL1 | |
| Hydrochloric Acid SCHEMBL6215660 | 0.86 | KDM4E (0.42) | KMT2ATHRBKDM4ESMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL6217243 | 0.86 | CYP2C19 (0.44) | KMT2ASMN1; SMN2MEN1CYP2C19L3MBTL1 | |
| SCHEMBL6218151 | 0.84 | SMN1; SMN2 (0.52) | KMT2ATHRBKDM4ESMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL6214106 | 0.83 | SMN1; SMN2 (0.51) | KMT2ATHRBKDM4ESMN1; SMN2MEN1 | |
| Pyridine SCHEMBL7179770 | 0.76 | MEN1 (0.38) | KMT2ATHRBKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL6215452 | 0.76 | ALDH1A1 (0.47) | KMT2AKDM4ESMN1; SMN2MEN1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129690-B1 | Keratin fibre dye compositions containing indolizine cationic derivatives and dyeing method | OREAL (FR) | 2005-01-05 | — | — | EP | claimed |
| EP-1129690-A2 | Keratin fibre dye compositions containing indolizine cationic derivatives and dyeing method | L'OREAL (FR) | 2001-09-05 | — | — | EP | claimed |
| EP-1129690-B1 | Keratin fibre dye compositions containing indolizine cationic derivatives and dyeing method | OREAL (FR) | 2005-01-05 | — | — | EP | disclosed |
| EP-1129690-A2 | Keratin fibre dye compositions containing indolizine cationic derivatives and dyeing method | L'OREAL (FR) | 2001-09-05 | — | — | EP | disclosed |