Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6214106 | 0.99 | SMN1; SMN2 (0.51) | SMN1; SMN2THRBL3MBTL1MAPTHTT | |
| SCHEMBL6216242 | 0.86 | MAPT (0.49) | SMN1; SMN2THRBL3MBTL1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL6215104 | 0.85 | MAPT (0.48) | SMN1; SMN2THRBL3MBTL1MAPTALDH1A1 | |
| SCHEMBL6213465 | 0.84 | KMT2A (0.40) | SMN1; SMN2THRBL3MBTL1MAPTHTT | |
| SCHEMBL6213516 | 0.84 | SMN1; SMN2 (0.54) | SMN1; SMN2THRBL3MBTL1MAPTHTT | |
| Hydrochloric Acid SCHEMBL6215709 | 0.83 | KMT2A (0.40) | SMN1; SMN2THRBL3MBTL1MAPTHTT | |
| Hydrochloric Acid SCHEMBL6214006 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2THRBL3MBTL1MAPTHTT | |
| SCHEMBL6217295 | 0.80 | THRB (0.47) | SMN1; SMN2THRBL3MBTL1MAPTHTT | |
| Hydrochloric Acid SCHEMBL6217535 | 0.79 | THRB (0.47) | SMN1; SMN2THRBL3MBTL1MAPTHTT | |
| SCHEMBL11074803 | 0.75 | SMN1; SMN2 (0.58) | SMN1; SMN2THRBL3MBTL1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129690-B1 | Keratin fibre dye compositions containing indolizine cationic derivatives and dyeing method | OREAL (FR) | 2005-01-05 | — | — | EP | claimed |
| EP-1129690-A2 | Keratin fibre dye compositions containing indolizine cationic derivatives and dyeing method | L'OREAL (FR) | 2001-09-05 | — | — | EP | claimed |
| EP-1129690-B1 | Keratin fibre dye compositions containing indolizine cationic derivatives and dyeing method | OREAL (FR) | 2005-01-05 | — | — | EP | disclosed |
| EP-1129690-A2 | Keratin fibre dye compositions containing indolizine cationic derivatives and dyeing method | L'OREAL (FR) | 2001-09-05 | — | — | EP | disclosed |