Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6215660 | 0.99 | KDM4E (0.42) | KDM4EALDH1A1LMNATHRBSMN1; SMN2 | |
| SCHEMBL6213465 | 0.87 | KMT2A (0.40) | KDM4EALDH1A1LMNATHRBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6215709 | 0.86 | KMT2A (0.40) | KDM4EALDH1A1LMNATHRBSMN1; SMN2 | |
| SCHEMBL6215452 | 0.85 | ALDH1A1 (0.47) | KDM4EALDH1A1LMNASMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL6216599 | 0.84 | ALDH1A1 (0.48) | KDM4EALDH1A1LMNASMN1; SMN2KMT2A | |
| SCHEMBL6213516 | 0.80 | SMN1; SMN2 (0.54) | KDM4EALDH1A1LMNATHRBSMN1; SMN2 | |
| SCHEMBL6214878 | 0.78 | KMT2A (0.54) | KDM4EALDH1A1LMNATHRBKMT2A | |
| SCHEMBL6221031 | 0.77 | LMNA (0.38) | KDM4EALDH1A1LMNATHRBSMN1; SMN2 | |
| Pyridine SCHEMBL7179770 | 0.77 | MEN1 (0.38) | KDM4EALDH1A1LMNATHRBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6218147 | 0.76 | LMNA (0.37) | KDM4EALDH1A1LMNATHRBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1129690-B1 | Keratin fibre dye compositions containing indolizine cationic derivatives and dyeing method | OREAL (FR) | 2005-01-05 | — | — | EP | claimed |
| EP-1129690-A2 | Keratin fibre dye compositions containing indolizine cationic derivatives and dyeing method | L'OREAL (FR) | 2001-09-05 | — | — | EP | claimed |
| EP-1129690-B1 | Keratin fibre dye compositions containing indolizine cationic derivatives and dyeing method | OREAL (FR) | 2005-01-05 | — | — | EP | disclosed |
| EP-1129690-A2 | Keratin fibre dye compositions containing indolizine cationic derivatives and dyeing method | L'OREAL (FR) | 2001-09-05 | — | — | EP | disclosed |